medAge Biltmore Park · Suite 218, Asheville NC · Call 828-684-1212
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PROVOQUE is not another serum from a brand. It is a peer-reviewed, clinically proven regenerative treatment co-founded by the physician who built medAge. Available here — and almost nowhere else in Western North Carolina.
Book a Skin Consultation
Now Available at medAge
Questions about PROVOQUE? Contact our clinical lead, Dr. Sarah Long, DNP, FNP-BC, for a consultation before purchasing. PROVOQUE is a physician-founded, physician-dispensed product — we're here to make sure it's right for you.
Dr. Laura Ellis has spent more than 20 years at the intersection of medicine and aesthetics — founding medAge, building one of the first independent vein surgery and aesthetic centers in the country, and publishing research in peer-reviewed journals including Plastic and Reconstructive Surgery. Her entire career has been built on one question: what does the evidence actually say?
When she met Hans Keirstead, PhD — a world-renowned stem cell scientist at AiVita Biomedical — the answer to that question became PROVOQUE. Together they co-founded LevEllis and brought to market a topical serum backed by an IRB-approved clinical trial and published in the Journal of Drugs in Dermatology. It is the only skincare product available at medAge that Dr. Ellis didn't just recommend — she helped build it.
"Your skin is born with the power to restore itself. Over time, that ability fades. PROVOQUE reawakens it."
Hans Keirstead, PhD — World-renowned stem cell scientist and regenerative medicine expert. His discovery of the complete skin progenitor secretome is the scientific foundation of PROVOQUE.
Most serums contain one or two growth factors. PROVOQUE contains the complete skin secretome — the full set of biological signals that young, healthy skin uses to repair and renew itself. That difference is not a marketing distinction. It is measurable in clinical data.
Hundreds of growth factors and exosomes — the individual biochemical messages that signal skin cells to repair damage, produce collagen, and renew themselves. Most serums contain a handful. PROVOQUE contains the complete profile.
Fetuin-A is a glycoprotein only secreted in significant quantities by very young cells. It carries growth factors deep into the skin, restores the calcium gradient in the epidermis, and has anti-inflammatory, anti-scarring, and barrier-restoring effects. No other skincare product contains it.
An exclusive blend of antioxidants, hyaluronic acid, and naturally occurring proteins and peptides work alongside the secretome to protect, hydrate, and revitalize. Preservative-free, paraben-free, fragrance-free, cruelty-free.
The study was published in the Journal of Drugs in Dermatology (May 2016). Subjects were assessed at weeks 2, 4, 8, and 12 by a dermatologist blind to the treatment. Every parameter showed statistically significant improvement by week 8.
Dermatologist-assessed improvement in skin health at week 12. *Nistor G, et al. J Drugs Dermatol. 2016;15(5):583-598.
Punch biopsies from treated skin were analyzed histologically. The results confirmed that PROVOQUE doesn't just improve how skin looks — it changes what the skin is doing at a cellular level.
Energy-based treatments like Morpheus8, CO2 laser, and RF microneedling work by creating controlled injury that triggers collagen remodeling. PROVOQUE amplifies that process — before, to prime the skin's regenerative signaling, and after, to coordinate repair. Our providers recommend it as part of every device treatment plan at medAge.
PROVOQUE is not a replacement for devices — it is a biologic coordination layer that enhances procedural outcomes through signal optimization.
Every skincare recommendation at medAge comes from a clinical conversation — not a product menu. Dr. Long and Madison each bring a different perspective to skin health. Together, they cover everything from a whole-body clinical assessment of what your skin is doing and why, to your first-ever skincare routine and how your injectables and skincare work together.
Dr. Long brings a whole-body clinical lens to skincare that most aesthetic practices don't offer. As a board-certified Family Nurse Practitioner with advanced training in functional and longevity medicine, she understands that skin health is rarely just a topical problem — it reflects hormonal status, metabolic function, and systemic inflammation. She pairs PROVOQUE with a clinical picture, not just a skin type. If your skin concerns feel deeper than what topicals alone can address, Dr. Long is who you want to see.
Madison is the provider patients turn to when they're building a skincare routine for the first time or want to understand how their injectables and skincare work together. Her dual background in exercise science and nursing — App State then Western Carolina University — gives her a uniquely practical perspective on skin health. If you've ever wanted someone to help you actually understand what you're using and why, without pressure or overwhelm, Madison is that person.
Every skincare recommendation at medAge begins with understanding your skin type, your concerns, your current routine, and your goals. We don't hand you a product; we build you a plan.
medAge carries PROVOQUE, Noon Aesthetics, and Neocutis. Every product in this practice was selected by Dr. Ellis and Dr. Long based on what the evidence says — not what a sales rep says.
At medAge, your skincare routine isn't separate from your injectables or your device treatments. It's part of the same conversation. PROVOQUE before Morpheus8. The right moisturizer after CO2. A routine that actually accounts for what your skin is going through.
We don't upsell. We don't push products patients don't need. If PROVOQUE is right for your skin, we'll tell you exactly why and show you the data. If something else is a better fit, that's what we'll recommend.
Book a skincare consultation at medAge. We'll assess your skin, walk you through what PROVOQUE does and whether it's right for you, and build a plan that fits your goals and your current routine.
PROVOQUE is a physician-founded, physician-dispensed product available at medAge. Our clinical lead Dr. Sarah Long, DNP, FNP-BC is available for consultation prior to purchase. Book above or call us directly.
medAge Customized Medicine & Aesthetics · Biltmore Park Town Square, Suite 218 · Asheville, NC 28803
